What can we learn from Fatima's case?
Effective multidisciplinary coordination
is imperative when treating IFIs
22,23
Optimal management of a patient with IFI requires
effective teamwork.
22,23 A multidisciplinary team
was involved in Fatima's care, with input from the
infectious diseases, ICU, radiology, neurosurgery,
mycology and histopathology teams.
Be aware of breakthroughs IFIs24
Breakthrough IFIs can still occur despite antifungal
prophylaxis. In Fatima's case, she had not been
taking her full prescribed dose of posaconazole
(300 mg qd prescribed, 200 mg qd taken),
resulting in sub-optimal prophylaxis and increased
risk of breakthrough infection.
25
Rapid implementation of diagnostic tests and
timely treatment are important. Lack of definitive
disease confirmation often causes delays in
commencing treatment, increasing the risk of
IFI-associated mortality.
1,12
Prompt treatment is key to ensuring
favourable outcomes
1–3
Effective multidisciplinary coordination is imperative when treating IFIs22,23
Be aware of breakthroughs IFIs24
Optimal management of a patient with IFI requires effective teamwork.22,23 A multidisciplinary team was involved in
Fatima's care, with input from the infectious diseases, ICU, radiology, neurosurgery, mycology and histopathology teams.
Breakthrough IFIs can still occur despite antifungal prophylaxis. In Fatima's case, she had not been taking her full prescribed
dose of posaconazole (300 mg qd prescribed, 200 mg qd taken), resulting in sub-optimal prophylaxis and increased risk of
breakthrough infection.
25
Rapid implementation of diagnostic tests and timely treatment are important. Lack of definitive disease confirmation often
causes delays in commencing treatment, increasing the risk of IFI-associated mortality.
1,12
What can we learn from Fatima's case?
Prompt treatment is key to ensuring favourable outcomes1–3